RA-Sr. RA-Antibody Screening and Characterization
Prellis Biologics
New Orleans, LA, USA
Posted on Jun 10, 2025
Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro antibody libraries andinvitrohumanlymphnodecoculturesfor generating antigen-specific B-cells.We are seeking a Research Associate – Senior Research Associate, Antibody Screening and Characterization to join our Antibody Screening team.This role will report to the Scientist heading antibody screening, with accountability for supporting small-scale protein purification and high-throughput antibody screening and characterization efforts, particularly using SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) technologies.
- Key Responsibilities:
- Execute high-throughput small-scale protein purification and analytical/QC workflows to generate high quality antibody samples.
- Support antibody discovery programs by running antibody screening assays using BLI (Octet) and SPR (Carterra) platforms to assess binding kinetics, affinity, and specificity.
- Analyze, interpret, and present kinetic data to inform antibody selection and optimization decisions.
- Independently troubleshoot and optimize experimental protocols for improved throughput, accuracy, and reproducibility.
- Maintain meticulous experimental records and effectively communicate findings in internal meetings.
- Qualifications:
- B.S in Molecular Biology, Chemistry, Immunology, Biotechnology, or related life science field with 4+ years of experience, or M.S. with 2+ years of relevant experience.
- Hands-on experience with BLI (Octet) and/or SPR (Carterra, Biacore) platforms is required.
- Proficient in small-scale protein purification, protein quantification, and analytical methods such as SDS-PAGE and SEC.
- Ideal candidates will have prior experience supporting antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
- Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment.
- Excellent communication skills and ability to document and present experimental results.
- Experience with automation platforms (liquid handlers) is a strong plus.