RA/Sr. RA
Prellis Biologics
This job is no longer accepting applications
See open jobs at Prellis Biologics.See open jobs similar to "RA/Sr. RA" Khosla Ventures.Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate in vitro antibody libraries andinvitrohumanlymphnodecoculturesfor generating antigen-specific B-cells.We are seeking a Research Associate – Senior Research Associate, Antibody Screening and Characterization to join our Antibody Screening team.This role will report to the Scientist heading antibody screening, with accountability for supporting small-scale protein purification and high-throughput antibody screening and characterization efforts, particularly using SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) technologies.
Key Responsibilities:
- Perform high-throughput small-scale protein purification and QC/analytics protocols, including SDS-PAGE, affinity chromatography and size-exclusion chromatography, to obtain highly pure antibody preparations.
- Support high-throughput antibody screening and characterization using BLI and SPR technologies to assess binding kinetics, specificity, and affinity, to support multiple antibody discovery projects.
- Independently troubleshoot and contribute to protocol optimization for enhanced efficiency and increased throughput.
- Collaborate with cross-functional teams, providing technical support for various projects requiring automated workflows.
- Maintain accurate records of experiments, analyze data, and present results in team meetings.
- Qualifications
- B.S in Molecular Biology, Chemistry, Immunology, Biotechnology, or related life science field with 4+ years of experience, or M.S. with 2+ years of relevant experience.
- Strong proficiency in antibody screening and characterization workflows, including protein quantification, purification, and characterization methods.
- Hands-on experience in small-scale protein purification using chromatography resins and antibody screening using BLI technique, such as Octet®. Familiarity with Carterra® LSA/LSAXT SPR is a strong plus.
- Ideal candidates will have prior experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
- Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment
- Excellent communication skills and ability to document and present experimental results.
- Experience with liquid-handling robots and other automation equipment is a strong plus.
This job is no longer accepting applications
See open jobs at Prellis Biologics.See open jobs similar to "RA/Sr. RA" Khosla Ventures.