Medical Affairs Research Manager
United States · Remote
USD 164,900-226,750 / year
Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Position Summary:
The Medical Research Manager will engage with top Key Opinion Leaders (KOLs) to inform research strategy, foster research collaboration, and promote scientific excellence. They will manage research proposals from the national Field Medical Team to support data generation and research activities for key applications and/or cancer types aligned with company initiatives across academic and community clinicians.
The Medical Research Manager will partner with multiple internal cross-functional stakeholders (Product, Technology Development and Bioinformatics, Clinical Development, Biostatistics, Managed Care and Reimbursement, Commercial) as well as external collaborators, advisors, and KOLs to identify clinical unmet need and evidence gaps to then lead the execution, and publication of clinical feasibility and validation studies, including those focused on clinical feasibility, clinical validity, and clinical utility. Additionally, the Medical Evidence Manager will perform direct research and develop scientific content for internal and external audiences.
Essential Duties and Responsibilities
- Establish and maintain relationships with top key opinion leaders for scientific exchange, elevating Guardant’s reputation and laying foundation for potential collaborations.
- Identify and pursue opportunities for collaboration, with input and oversight by leadership, with top key opinion leaders and their institutions that support Guardant Health strategic clinical data development needs.
- Collaborate with area lead to address inbound research requests from Field Medical partners to promote deeper understanding of Guardant research practices and strategies
- Identify clinical unmet needs, evidence gaps and execute evidence-generating studies to support development, commercial launch, reimbursement, and guideline adoption of the Guardant 360 Liquid and Tissue products
- Leverage scientific, clinical, and/or technical expertise to influence top key opinion leaders biomarker implementation for their clinical trials and interpretation of Guardant Research Use Only (RUO) and Investigative Use Only (IUO) data returned.
- Conduct research with Guardant datasets alongside collaborators and champion effective scientific writing for effective data submissions to peer-reviewed
- Provide strategic review and proposed edits for collaborative abstracts, posters, presentations and manuscripts when applicable
- Serve as internal and external advocate for scientifically and clinically sound applications of ctDNA for clinical trials, oncology research and future clinical care
- Generates accurate and up-to-date scientific and medical content, including late-stage treatment landscapes for application/cancer type/s accountable for, for internal and external audiences
- Maintains awareness of related publications across platforms and generates up-to-date scientific and medical content for applications/cancer type/s accountable for
Qualifications:
- Typically requires a university degree and typically 8 years of related experience; 6 years and a Master’s degree; 3 years and a PhD; or PharmD/MD. Clinical expertise or related experience in oncology and/or genomics is highly desirable.
- Experience working with experts at academic medical centers and/or biopharma companies to build consensus around new products and/or services highly desirable.
- Experience designing, conducting, and/or publishing clinical research required
- Proven experience developing and generating data for novel clinical products with KOLs strongly desired
Technical Skills Required:
- Expertise in genomic biomarker testing technologies, including IHC, DNA/RNA, FISH, NGS (particularly plasma NGS/liquid biopsy), and digital PCR
- Applies advanced knowledge of the biotechnology, diagnostics and pharmaceutical industry.
- Ability to apply advanced knowledge of company product specifications.
- Intermediate-to-advanced knowledge of the following computer software programs: Microsoft Office: Powerpoint, Excel, and Word
- Ability to work independently and remotely while maintaining a strong teamwork ethic.
Work Environment:
- Moderate travel required, approximately 3-5 trips per quarter to meet with KOLs/PIs, attend conferences, including specialty society scientific meetings (will require some weekend work), and trips to headquarters. Travel is estimated to be up to 40%.
- Must be physically able to handle travel in vehicle, plane, or other modes of public transport.
- Office may be home-based, and involves extensive use of computer and keyboard while in home office.
- Requires the ability to focus on multiple tasks simultaneously, work in high-paced, high-energy environment and the ability to work independently and remotely while maintaining a strong teamwork ethic.
AI & Digital Fluency
- Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.
Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
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Please visit our career page at: http://www.guardanthealth.com/jobs/