People Matter

Senior Automation Engineer

Guardant Health

Guardant Health

Software Engineering
Palo Alto, CA, USA
Posted on Wednesday, June 26, 2024

Company Description

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs across all stages of the cancer care continuum. Guardant Health has commercially launched Guardant360®, Guardant360 CDx, Guardant360 TissueNext™, Guardant360 Response™, and GuardantOMNI® tests for advanced stage cancer patients, and Guardant Reveal™ for early-stage cancer patients. The Guardant Health screening portfolio, including the Shield™ test, aims to address the needs of individuals eligible for cancer screening.

Job Description

About the Role:

We are seeking a scientist or engineer with a proven track record in automation and scaling, eager to take part in the development of a high-growth, fast-paced, automated laboratory.

The ideal candidate will have an interdisciplinary background in molecular biology, lab automation, and programming, with experience in designing, developing, testing, implementing, and supporting automated sample-processing workflows.

The ideal candidate has a background in a requirements-driven approaches within a clinical laboratory or molecular biology-based laboratory.

Essential Duties and Responsibilities:

  • Apply scientific methods and engineering skills in efforts for scalability sample processing workflows.
  • Collaborate or lead cross-functional teams working in a variety of projects to explore, develop, optimize, test, and put in place scalable solutions for sample processing workflows.
  • Demonstrate a solid understanding of business and user requirements and improving efficiency, throughput, and quality of processes.
  • Contribute to protocol generation, report writing, and presentation preparation.
  • Program, and troubleshoot liquid handling robotics platforms for whole blood separation - preferably on a Hamilton platform.
  • Integrate automated methods with sample tracking and data management software (is a plus)


  • BS degree in Mechanical Engineering, Biomedical Engineering, Bioengineering, Chemical Engineering or a closely related discipline, with 5+ years of related experience or MS with 3+ years of related work experience will also be considered.
  • Experience streamlining workflows, developing automated laboratory processes, and instrumentation systems, from concept generation. As well as requirements gathering through to process validation and implementation.
  • Experience with programming liquid handling robotics platforms (Hamilton, Agilent)
  • Basic programming knowledge of Python, C# or relevant similar languages
  • Experience in automated development of next-generation sequencing (NGS) assays and/or standard molecular biology techniques. (ie: nucleic acid isolation and purification, DNA quantitation, PCR, etc.)
  • Verification & Validation experience, URS, IQ, OQ, PQ, FAT, SAT, pFMEA, and technical files for submission
  • Experience working within regulated environments (IVD, LDT, etc.)
  • Strong communication and collaborative skills
  • Ability to work, internal & external with diverse scientific, engineering, operational, and regulatory disciplines.
  • Experience with statistical data analysis, monitoring data quality, and troubleshooting technical problems.

Additional Information

For positions based in Palo Alto, CA or Redwood City, CA, the base salary range for this full-time position is $122,000 to $164,700. The range does not include benefits, and if applicable, bonus, commission, or equity.

Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [email protected]

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

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